We are a U.S.-based Active Pharmaceutical Ingredient (API) manufacturer focused on producing the essential building blocks of modern medicine. Every great medication begins with a high-quality ingredient, and that’s exactly what we deliver. By manufacturing APIs domestically, we help strengthen America’s pharmaceutical supply chain and ensure reliable access to critical ingredients.
Powering the Future of U.S. Pharmaceutical Manufacturing
Meet Sentinel API Group
What are API’s?
An Active Pharmaceutical Ingredient (API) is the biologically active substance in a medication that yields the desired clinical effect (for example, Metformin in diabetes drugs or Amoxicillin in antibiotics).
Every finished drug product (the tablet, capsule, or injection) is composed of two parts:
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API — the active compound that treats the condition.
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Excipient — the inactive substance used as a carrier or filler.
APIs are the active parts of a medicine — the components that make it work. From pain relief and infection control to hormone support and chronic disease management, our APIs power the treatments that improve lives every day.
We specialize in producing these active ingredients for use in tablets, capsules, creams, and injectables supplied to pharmacies and healthcare facilities across the country.
Rebuilding America’s API Infrastructure—One Molecule at a Time
100% U.S.-Based Manufacturing
Commitment to Quality
Our facilities follow cGMP and use advanced equipment to ensure purity, consistency, and safety — from raw materials to finished product.
Innovation and Technology
Our Mission
We partner with pharmaceutical companies and compounders who rely on our ingredients to make life-changing medicines. Our APIs are used in products that reach hospitals, pharmacies, and patients across the U.S. and beyond.
Our partners trust us because we deliver what matters most — quality, consistency, and reliability.
Meet Our Founders



Leading the Renaissance of American API Manufacturing
Disclaimer:
All images, renderings, and videos displayed on this website are for illustrative and visualization purposes only. They are conceptual representations intended to convey design intent and operational vision and do not depict actual Sentinel API Group facilities, equipment, or production environments. Final facility specifications and operations will conform to applicable FDA, GMP, and federal regulatory standards upon completion.












